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Recombinant activated protein C in sepsis: endothelium protection or endothelium therapy?

Endothelium dysfunction is one of the hallmarks of sepsis. Looney and Mattay, in the previous issue of Critical Care, highlight the role of activated protein C (APC) as a protective endothelial drug in septic situations. Nevertheless, the results of in vivo studies are less explicit and it remains u...

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Detalhes bibliográficos
Main Authors: Regnault, Veronique, Levy, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151861/
https://ncbi.nlm.nih.gov/pubmed/17224039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc5135
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