The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

INTRODUCTION: Activated protein C (APC) induces release of microparticles (MP) from primary physiological cells, which are found in patients undergoing treatment with recombinant human APC (rhAPC) for severe sepsis. We hypothesised that APC on these circulating MPs activate endothelial protease-acti...

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Detalhes bibliográficos
Main Authors: Pérez-Casal, Margarita, Thompson, Victoria, Downey, Colin, Welters, Ingeborg, Wyncoll, Duncan, Thachil, Jecko, Toh, Cheng Hock
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387637/
https://ncbi.nlm.nih.gov/pubmed/21834973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10356
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