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The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

INTRODUCTION: Activated protein C (APC) induces release of microparticles (MP) from primary physiological cells, which are found in patients undergoing treatment with recombinant human APC (rhAPC) for severe sepsis. We hypothesised that APC on these circulating MPs activate endothelial protease-acti...

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書誌詳細
主要な著者: Pérez-Casal, Margarita, Thompson, Victoria, Downey, Colin, Welters, Ingeborg, Wyncoll, Duncan, Thachil, Jecko, Toh, Cheng Hock
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387637/
https://ncbi.nlm.nih.gov/pubmed/21834973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10356
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