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Sequence dependent modulating effect of camptothecin on the DNA-cleaving activity of the calf thymus type I topoisomerase.

High-resolution mapping of topol cleavages in the regions of human DNA including the oncogene c-Ha-ras and p53, has revealed three kinds of topol cleavage sites: cleavage sites not affected by camptothecin; cleavage sites reinforced only in the presence of camptothecin, and cleavage sites which weak...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Gromova, I I, Buchman, V L, Abagyan, R A, Ulyanov, A V, Bronstein, I B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1990
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2155407/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.3.637
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