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Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

The hypoxia inducible transcription factors (HIFs) control many mediators of vascular response, including both angiogenic factors and small molecules such as nitric oxide (NO). In studying how endothelial HIF response itself affects metastasis, we found that loss of HIF-1α in endothelial cells reduc...

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Detalhes bibliográficos
Main Authors: Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334270/
https://ncbi.nlm.nih.gov/pubmed/22264788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.11.017
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