Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

The hypoxia inducible transcription factors (HIFs) control many mediators of vascular response, including both angiogenic factors and small molecules such as nitric oxide (NO). In studying how endothelial HIF response itself affects metastasis, we found that loss of HIF-1α in endothelial cells reduc...

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Autori principali: Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334270/
https://ncbi.nlm.nih.gov/pubmed/22264788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.11.017
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