Loss of fibroblast HIF-1α accelerates tumorigenesis

Solid tumors consist of malignant cells and associated stromal components, including fibroblastic cells that contribute to tumor growth and progression. Although tumor fibrosis and aberrant vascularization contribute to the hypoxia often found in advanced tumors, the contribution of hypoxic signalin...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kim, Jung-whan, Evans, Colin, Weidemann, Alexander, Takeda, Norihiko, Lee, Yun Sok, Stockmann, Christian, Branco-Price, Cristina, Brandberg, Filip, Leone, Gustavo, Ostrowski, Michael C., Johnson, Randall S.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089958/
https://ncbi.nlm.nih.gov/pubmed/22556263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0534
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