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Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases
Targeted gene addition to mammalian genomes is central to biotechnology, basic research and gene therapy. For example, gene targeting to the ROSA26 locus by homologous recombination in embryonic stem cells is commonly used for mouse transgenesis to achieve ubiquitous and persistent transgene express...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3333879/ https://ncbi.nlm.nih.gov/pubmed/22169954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1214 |
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