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Design, Synthesis and Biological Action of 20R-Hydroxyvitamin D3

Non-naturally occurring 20R epimer of 20-hydroxyvitamin D3 is synthesized based on chemical design and hypothesis. The 20R isomer is separated from semi-preparative HPLC and its structure is characterized. The comparison of 20R isomer to its 20S counterpart in biological evaluation demonstrates they...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lu, Yan, Chen, Jianjun, Janjetovic, Zorica, Michaels, Phillip, Tang, Edith K Y, Wang, Jin, Tuckey, Robert C., Slominski, Andrzej T., Li, Wei, Miller, Duane D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332540/
https://ncbi.nlm.nih.gov/pubmed/22404326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201478e
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