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Chemical synthesis of 20S-hydroxyvitamin D3, which shows anti-proliferative activity
20S-hydroxyvitamin D3 (20S-(OH)D3), an in vitro product of vitamin D3 metabolism by the cytochrome P450scc, was recently isolated, identified and shown to possess antiproliferative activity without inducing hypercalcemia. The enzymatic production of 20S-(OH)D3 is tedious, expensive, and cannot meet...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937189/ https://ncbi.nlm.nih.gov/pubmed/20542050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2010.05.021 |
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