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Chemical synthesis of 20S-hydroxyvitamin D3, which shows anti-proliferative activity

20S-hydroxyvitamin D3 (20S-(OH)D3), an in vitro product of vitamin D3 metabolism by the cytochrome P450scc, was recently isolated, identified and shown to possess antiproliferative activity without inducing hypercalcemia. The enzymatic production of 20S-(OH)D3 is tedious, expensive, and cannot meet...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Li, Wei, Chen, Jianjun, Janjetovic, Zorica, Kim, Tae-Kang, Sweatman, Trevor, Lu, Yan, Zjawiony, Jordan, Tuckey, Robert C, Miller, Duane, Slominski, Andrzej
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937189/
https://ncbi.nlm.nih.gov/pubmed/20542050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2010.05.021
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