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Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing
The tandem PHD finger–bromodomain, found in many chromatin-associated proteins, has an important role in gene silencing by the human co-repressor KRAB-associated protein 1 (KAP1). Here we report the three-dimensional solution structure of the tandem PHD finger–bromodomain of KAP1. The structure reve...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331790/ https://ncbi.nlm.nih.gov/pubmed/18488044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1416 |
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