Epigenetic Gene Silencing by the SRY Protein Is Mediated by a KRAB-O Protein That Recruits the KAP1 Co-repressor Machinery

The sex determination transcription factor SRY is a cell fate-determining transcription factor that mediates testis differentiation during embryogenesis. It may function by repressing the ovarian determinant gene, RSPO1, action in the ovarian developmental pathway and activates genes, such as SOX9,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peng, Hongzhuang, Ivanov, Alexey V., Oh, Hyun J., Lau, Yun-Fai C., Rauscher, Frank J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Transcription, Chromatin, and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790998/
https://ncbi.nlm.nih.gov/pubmed/19850934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032086
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