Epigenetic Gene Silencing by the SRY Protein Is Mediated by a KRAB-O Protein That Recruits the KAP1 Co-repressor Machinery

The sex determination transcription factor SRY is a cell fate-determining transcription factor that mediates testis differentiation during embryogenesis. It may function by repressing the ovarian determinant gene, RSPO1, action in the ovarian developmental pathway and activates genes, such as SOX9,...

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Bibliografiske detaljer
Main Authors: Peng, Hongzhuang, Ivanov, Alexey V., Oh, Hyun J., Lau, Yun-Fai C., Rauscher, Frank J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Transcription, Chromatin, and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790998/
https://ncbi.nlm.nih.gov/pubmed/19850934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032086
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