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Functional Analysis of KAP1 Genomic Recruitment

TRIM28 (KAP1) is upregulated in many cancers and has been implicated in both transcriptional activation and repression. Using chromatin immunoprecipitation and sequencing, we show that KAP1 binding sites fall into several categories, specifically, the 3′ coding exons of zinc finger (ZNF) genes and p...

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Bibliographische Detailangaben
Hauptverfasser: Iyengar, Sushma, Ivanov, Alexey V., Jin, Victor X., Rauscher, Frank J., Farnham, Peggy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133220/
https://ncbi.nlm.nih.gov/pubmed/21343339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01331-10
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