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Genome-wide Analysis of Transcription Factor E2F1 Mutant Proteins Reveals That N- and C-terminal Protein Interaction Domains Do Not Participate in Targeting E2F1 to the Human Genome

Previous studies of E2F family members have suggested that protein-protein interactions may be the mechanism by which E2F proteins are recruited to specific genomic regions. We have addressed this hypothesis on a genome-wide scale using ChIP-seq analysis of MCF7 cell lines that express tagged wild t...

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Detalhes bibliográficos
Main Authors: Cao, Alina R., Rabinovich, Roman, Xu, Maoxiong, Xu, Xiaoqin, Jin, Victor X., Farnham, Peggy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069401/
https://ncbi.nlm.nih.gov/pubmed/21310950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.217158
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