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Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2α subunit of NuRD

Macromolecular complexes containing histone deacetylase and ATPase activities regulate chromatin dynamics and are vitally responsible for transcriptional gene silencing in eukaryotes. The mechanisms that target these assemblies to specific loci are not as well understood. We show that the corepresso...

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Detalhes bibliográficos
Publicado no:Genes Dev
Principais autores: Schultz, David C., Friedman, Josh R., Rauscher, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.869501
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