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Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

A novel histone methyltransferase, termed Set9, was isolated from human cells. Set9 contains a SET domain, but lacks the pre- and post-SET domains. Set9 methylates specifically lysine 4 (K4) of histone H3 (H3-K4) and potentiates transcription activation. The histone H3 tail interacts specifically wi...

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Detalhes bibliográficos
Main Authors: Nishioka, Kenichi, Chuikov, Sergei, Sarma, Kavitha, Erdjument-Bromage, Hediye, Allis, C. David, Tempst, Paul, Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155346/
https://ncbi.nlm.nih.gov/pubmed/11850410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.967202
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