Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

A novel histone methyltransferase, termed Set9, was isolated from human cells. Set9 contains a SET domain, but lacks the pre- and post-SET domains. Set9 methylates specifically lysine 4 (K4) of histone H3 (H3-K4) and potentiates transcription activation. The histone H3 tail interacts specifically wi...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Nishioka, Kenichi, Chuikov, Sergei, Sarma, Kavitha, Erdjument-Bromage, Hediye, Allis, C. David, Tempst, Paul, Reinberg, Danny
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2002
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.967202
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