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Cyclic Peptide Inhibitors of HIV-1 Capsid-Human Lysyl-tRNA Synthetase Interaction
[Image: see text] The human immunodeficiency virus type 1 (HIV-1) capsid protein (CA) plays a critical role in the viral life cycle. The C-terminal domain (CTD) of CA binds to human lysyl-tRNA synthetase (hLysRS), and this interaction facilitates packaging of host cell tRNA(Lys,3), which serves as t...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2012
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330833/ https://ncbi.nlm.nih.gov/pubmed/22276994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200450w |
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