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Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
In mammals, many aminoacyl-tRNA synthetases are bound together in a multisynthetase complex (MSC) as a reservoir of procytokines and regulation molecules for functions beyond aminoacylation. The α(2) homodimeric lysyl-tRNA synthetase (LysRS) is tightly bound in the MSC and, under specific conditions...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268136/ https://ncbi.nlm.nih.gov/pubmed/18272479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712072105 |
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