Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation

In mammals, many aminoacyl-tRNA synthetases are bound together in a multisynthetase complex (MSC) as a reservoir of procytokines and regulation molecules for functions beyond aminoacylation. The α(2) homodimeric lysyl-tRNA synthetase (LysRS) is tightly bound in the MSC and, under specific conditions...

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Detaylı Bibliyografya
Asıl Yazarlar: Guo, Min, Ignatov, Michael, Musier-Forsyth, Karin, Schimmel, Paul, Yang, Xiang-Lei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268136/
https://ncbi.nlm.nih.gov/pubmed/18272479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712072105
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