Anticodon-like binding of the HIV-1 tRNA-like element to human lysyl-tRNA synthetase

A critical step in the HIV-1 lifecycle involves reverse transcription of the viral genomic RNA (gRNA). Human tRNA(Lys3) serves as a primer for transcription initiation and is selectively enriched in virus particles. Human lysyl-tRNA synthetase (hLysRS) is also packaged into virions. Recently, a tRNA...

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Bibliographic Details
Published in:RNA
Main Authors: Liu, Sheng, Comandur, Roopa, Jones, Christopher P., Tsang, Pearl, Musier-Forsyth, Karin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113203/
https://ncbi.nlm.nih.gov/pubmed/27852925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058081.116
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