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Dual Role for Motif 1 Residues of Human Lysyl-tRNA Synthetase in Dimerization and Packaging into HIV-1

The primer for reverse transcription in human immunodeficiency virus type 1, human tRNA(Lys,3), is selectively packaged into the virion along with tRNA(Lys1,2). Human lysyl-tRNA synthetase (hLysRS), the only cellular factor known to interact specifically with all three tRNA(Lys) isoacceptors, is als...

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Hlavní autoři: Dewan, Varun, Wei, Min, Kleiman, Lawrence, Musier-Forsyth, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516742/
https://ncbi.nlm.nih.gov/pubmed/23095741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421842
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