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Formation of the tRNA(Lys) Packaging Complex in HIV-1

Human immunodeficiency virus 1 (HIV-1) uses a host cell tRNA(Lys,3) molecule to prime reverse transcription of the viral RNA genome into double-stranded DNA prior to integration into the host genome. All three human tRNA(Lys) isoacceptors along with human lysyl-tRNA synthetase (LysRS) are selectivel...

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Detalhes bibliográficos
Main Authors: Kleiman, Lawrence, Jones, Christopher, Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820394/
https://ncbi.nlm.nih.gov/pubmed/19914238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.038
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