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Molecular mimicry of human tRNA(Lys) anti-codon domain by HIV-1 RNA genome facilitates tRNA primer annealing
The primer for initiating reverse transcription in human immunodeficiency virus type 1 (HIV-1) is tRNA(Lys3). Host cell tRNA(Lys) is selectively packaged into HIV-1 through a specific interaction between the major tRNA(Lys)-binding protein, human lysyl-tRNA synthetase (hLysRS), and the viral protein...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543088/ https://ncbi.nlm.nih.gov/pubmed/23264568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036681.112 |
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