Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis

Increased myocardial extracellular matrix collagen represents an important structural milestone during the development of left ventricular (LV) pressure overload (PO); however, the proteolytic pathways that contribute to this process are not fully understood. This study tested the hypothesis that me...

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Bibliographic Details
Main Authors: Zile, Michael R., Baicu, Catalin F., Stroud, Robert E., Van Laer, An, Arroyo, Jazmine, Mukherjee, Rupak, Jones, Jeffrey A., Spinale, Francis G.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Signaling and Stress Response
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330784/
https://ncbi.nlm.nih.gov/pubmed/22287584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00580.2011
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