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RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter
The knowledge of molecular control mechanisms underlying the basal tone in the intact human internal anal sphincter (IAS) is critical for the pathophysiology and rational therapy for a number of debilitating rectoanal motility disorders. We determined the role of RhoA/ROCK and PKC pathways by compar...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330775/ https://ncbi.nlm.nih.gov/pubmed/22241857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00430.2011 |
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