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RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter

The knowledge of molecular control mechanisms underlying the basal tone in the intact human internal anal sphincter (IAS) is critical for the pathophysiology and rational therapy for a number of debilitating rectoanal motility disorders. We determined the role of RhoA/ROCK and PKC pathways by compar...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rattan, Satish, Singh, Jagmohan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330775/
https://ncbi.nlm.nih.gov/pubmed/22241857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00430.2011
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