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Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor

Clostridium difficile, a causative agent of antibiotic-associated diarrhea and its potentially lethal form, pseudomembranous colitis, produces two large protein toxins that are responsible for the cellular damage associated with the disease. The level of toxin production appears to be critical for d...

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Библиографические подробности
Главные авторы: Mani, Nagraj, Dupuy, Bruno
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC33301/
https://ncbi.nlm.nih.gov/pubmed/11320220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101126598
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