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Expression of Clostridium difficile Toxins A and B and Their Sigma Factor TcdD Is Controlled by Temperature

Growth temperature was found to control the expression of toxins A and B in Clostridium difficile VPI 10463, with a maximum at 37°C and low levels at 22 and 42°C in both peptone yeast (PY) and defined media. The up-regulation of toxin A and B mRNA and protein levels upon temperature upshift from 22...

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Detalhes bibliográficos
Main Authors: Karlsson, Sture, Dupuy, Bruno, Mukherjee, Kakoli, Norin, Elisabeth, Burman, Lars G., Åkerlund, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152060/
https://ncbi.nlm.nih.gov/pubmed/12654792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1784-1793.2003
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