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Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor

Clostridium difficile, a causative agent of antibiotic-associated diarrhea and its potentially lethal form, pseudomembranous colitis, produces two large protein toxins that are responsible for the cellular damage associated with the disease. The level of toxin production appears to be critical for d...

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Hlavní autoři: Mani, Nagraj, Dupuy, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC33301/
https://ncbi.nlm.nih.gov/pubmed/11320220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101126598
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