Environmental Response and Autoregulation of Clostridium difficile TxeR, a Sigma Factor for Toxin Gene Expression

TxeR, a sigma factor that directs Clostridium difficile RNA polymerase to recognize the promoters of two major toxin genes, was shown to stimulate its own synthesis. Whether expressed in C. difficile, Clostridium perfringens, or Escherichia coli, TxeR stimulated transcription of fusions of the txeR...

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Detalhes bibliográficos
Main Authors: Mani, Nagraj, Lyras, Dena, Barroso, Lisa, Howarth, Pauline, Wilkins, Tracy, Rood, Julian I., Sonenshein, Abraham L., Dupuy, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135396/
https://ncbi.nlm.nih.gov/pubmed/12374831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.21.5971-5978.2002
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