Environmental Response and Autoregulation of Clostridium difficile TxeR, a Sigma Factor for Toxin Gene Expression

TxeR, a sigma factor that directs Clostridium difficile RNA polymerase to recognize the promoters of two major toxin genes, was shown to stimulate its own synthesis. Whether expressed in C. difficile, Clostridium perfringens, or Escherichia coli, TxeR stimulated transcription of fusions of the txeR...

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Bibliographic Details
Main Authors: Mani, Nagraj, Lyras, Dena, Barroso, Lisa, Howarth, Pauline, Wilkins, Tracy, Rood, Julian I., Sonenshein, Abraham L., Dupuy, Bruno
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135396/
https://ncbi.nlm.nih.gov/pubmed/12374831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.21.5971-5978.2002
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