Proximal Ligand Electron Donation and Reactivity of the Cytochrome P450 Ferric-Peroxo Anion

CYP125 from Mycobacterium tuberculosis catalyzes sequential oxidation of the cholesterol side-chain terminal methyl group to the alcohol, aldehyde, and finally acid. Here, we demonstrate that CYP125 simultaneously catalyzes the formation of five other products, all of which result from deformylation...

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Detaylı Bibliyografya
Asıl Yazarlar: Sivaramakrishnan, Santhosh, Ouellet, Hugues, Matsumura, Hirotoshi, Guan, Shenheng, Moënne-Loccoz, Pierre, Burlingame, Alma L., Ortiz de Montellano, Paul R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329582/
https://ncbi.nlm.nih.gov/pubmed/22444582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211499q
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