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Proximal Ligand Electron Donation and Reactivity of the Cytochrome P450 Ferric-Peroxo Anion

CYP125 from Mycobacterium tuberculosis catalyzes sequential oxidation of the cholesterol side-chain terminal methyl group to the alcohol, aldehyde, and finally acid. Here, we demonstrate that CYP125 simultaneously catalyzes the formation of five other products, all of which result from deformylation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sivaramakrishnan, Santhosh, Ouellet, Hugues, Matsumura, Hirotoshi, Guan, Shenheng, Moënne-Loccoz, Pierre, Burlingame, Alma L., Ortiz de Montellano, Paul R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329582/
https://ncbi.nlm.nih.gov/pubmed/22444582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211499q
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