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In Situ Assembly of Octahedral Fe(II) Complexes for the Enantiomeric Excess Determination of Chiral Amines Using CD spectroscopy

A method for discriminating between α-chiral primary amine enantiomers is reported. The method utilizes circular dichroism spectroscopy and a sensing ensemble composed of 2-formyl-3-hydroxyl pyridine (4) and Fe(II)(TfO)(2). Aldehyde 4 reacts rapidly with chiral amines to form chiral imines, which co...

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Bibliografiske detaljer
Main Authors: Dragna, Justin, Pescitelli, Gennaro, Tran, Lee, Lynch, Vincent M., Anslyn, Eric V., Di Bari, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329375/
https://ncbi.nlm.nih.gov/pubmed/22272943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211768v
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