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Rapid Determination of Enantiomeric Excess of α–Chiral Cyclohexanones Using Circular Dichroism Spectroscopy

[Image: see text] Ketone handedness was discriminated using circular dichroism (CD) spectroscopy by monitoring the metal-to-ligand charge transfer (MLCT) bands of complexes between [Cu(I)((S)-1)(CH(3)CN)(2)]PF(6) and derivatized α-chiral cyclohexanones (4). This method was able to quantify enantiome...

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Detalhes bibliográficos
Main Authors: Leung, Diana, Anslyn, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097997/
https://ncbi.nlm.nih.gov/pubmed/21486023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2004885
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