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A Facile CD Protocol for Rapid Determination of Enantiomeric Excess and Concentration of Chiral Primary Amines

A protocol for the rapid determination of the absolute configuration and enantiomeric excess of α-chiral primary amines with potential applications in asymmetric reaction discovery has been developed. The protocol requires derivatization of α-chiral primary amines via condensation with pyridine carb...

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Bibliografiske detaljer
Main Authors: Nieto, Sonia, Dragna, Justin M., Anslyn, Eric V.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982703/
https://ncbi.nlm.nih.gov/pubmed/19946914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200902650
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