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A Facile CD Protocol for Rapid Determination of Enantiomeric Excess and Concentration of Chiral Primary Amines

A protocol for the rapid determination of the absolute configuration and enantiomeric excess of α-chiral primary amines with potential applications in asymmetric reaction discovery has been developed. The protocol requires derivatization of α-chiral primary amines via condensation with pyridine carb...

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Bibliografiska uppgifter
Huvudupphovsmän: Nieto, Sonia, Dragna, Justin M., Anslyn, Eric V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982703/
https://ncbi.nlm.nih.gov/pubmed/19946914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200902650
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