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IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells

Extracellular matrix accumulation contributes to the progression of chronic kidney disease. Many growth factors including insulin-like growth factor-I (IGF-I) enhance matrix protein accumulation. Proximal tubular epithelial cells (PTCs) synthesize matrix proteins. NADPH oxidases are major sources of...

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שמור ב:
מידע ביבליוגרפי
Main Authors: New, David D., Block, Karen, Bhandhari, Basant, Gorin, Yves, Abboud, Hanna E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328902/
https://ncbi.nlm.nih.gov/pubmed/21940672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00141.2011
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