Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes

Oxidative stress contributes to diabetic cardiomyopathy. This study explored the role of the NADPH oxidase Nox4 as a source of reactive oxygen species (ROS) involved in the development of diabetic cardiomyopathy. Phosphorothioated antisense (AS) or sense (S) oligonucleotides for Nox4 were administer...

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Main Authors: Maalouf, Rita M., Eid, Assaad A., Gorin, Yves C., Block, Karen, Escobar, Gladys Patricia, Bailey, Steven, Abboud, Hanna E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Receptors and Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814247/
https://ncbi.nlm.nih.gov/pubmed/22031600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00331.2011
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