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Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site.

A dodecadeoxyribonucleotide containing a cis-syn thymine dimer with a phosphorodithioate linkage was synthesized on a solid support using a dinucleotide coupling unit prepared by UV-irradiation of dithymidine monophosphorodithioate followed by S- and 5'-O-protection and 3'-phosphitylation....

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Detalhes bibliográficos
Main Authors: Murata, T, Iwai, S, Ohtsuka, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC332863/
https://ncbi.nlm.nih.gov/pubmed/2259623
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