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Catalysis and mechanistic insights on Sirtuin activation
SIRT1 is a member of the Sir2 family of NAD(+) dependent protein deacetylases. The central role of SIRT1 in multiple metabolic and aging-related pathways has pushed SIRT1 to the forefront for the discovery of small molecule activators. Promising compounds including resveratrol and SRT1720 have been...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327882/ https://ncbi.nlm.nih.gov/pubmed/21243715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000434 |
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