Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

Mammalian sirtuins (SIRT1 through SIRT7) are members of a highly conserved family of NAD(+)-dependent protein deacetylases that function in metabolism, genome maintenance, and stress responses. Emerging evidence suggests that some sirtuins display substrate specificity toward other acyl groups attac...

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Autors principals: Feldman, Jessica L., Baeza, Josue, Denu, John M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829447/
https://ncbi.nlm.nih.gov/pubmed/24052263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.511261
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