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Phospholemman is a Negative Feed-Forward Regulator of Ca(2+) in β-Adrenergic Signaling, Accelerating β-Adrenergic Inotropy
Sympathetic stimulation enhances cardiac contractility by stimulating β-adrenergic signaling and protein kinase A (PKA). Recently, phospholemman (PLM) has emerged as an important PKA substrate capable of regulating cytosolic Ca(2+) transients. However, it remains unclear how PLM contributes to β-adr...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327824/ https://ncbi.nlm.nih.gov/pubmed/22289214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.12.015 |
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