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Modeling the Effects of β(1)-Adrenergic Receptor Blockers and Polymorphisms on Cardiac Myocyte Ca(2+) Handling
β-Adrenergic receptor blockers (β-blockers) are commonly used to treat heart failure, but the biologic mechanisms governing their efficacy are still poorly understood. The complexity of β-adrenergic signaling coupled with the influence of receptor polymorphisms makes it difficult to intuit the effec...
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| Main Authors: | , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Pharmacology and Experimental
Therapeutics
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127930/ https://ncbi.nlm.nih.gov/pubmed/24867460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090951 |
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