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Modeling the Effects of β(1)-Adrenergic Receptor Blockers and Polymorphisms on Cardiac Myocyte Ca(2+) Handling

β-Adrenergic receptor blockers (β-blockers) are commonly used to treat heart failure, but the biologic mechanisms governing their efficacy are still poorly understood. The complexity of β-adrenergic signaling coupled with the influence of receptor polymorphisms makes it difficult to intuit the effec...

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Hlavní autoři: Amanfu, Robert K., Saucerman, Jeffrey J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127930/
https://ncbi.nlm.nih.gov/pubmed/24867460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090951
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