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PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling
β-adrenergic signaling is spatiotemporally heterogeneous in the cardiac myocyte, conferring exquisite control to sympathetic stimulation. Such heterogeneity drives the formation of protein kinase A (PKA) signaling microdomains, which regulate Ca(2+) handling and contractility. Here, we test the hypo...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3927644/ https://ncbi.nlm.nih.gov/pubmed/24225179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.11.001 |
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