B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

Wiskott Aldrich syndrome (WAS) is caused by mutations in the WAS gene that encodes for a protein (WASp) involved in cytoskeleton organization in hematopoietic cells. Several distinctive abnormalities of T, B, and natural killer lymphocytes; dendritic cells; and phagocytes have been found in WASp-def...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Recher, Mike, Burns, Siobhan O., de la Fuente, Miguel A., Volpi, Stefano, Dahlberg, Carin, Walter, Jolan E., Moffitt, Kristin, Mathew, Divij, Honke, Nadine, Lang, Philipp A., Patrizi, Laura, Falet, Hervé, Keszei, Marton, Mizui, Masayuki, Csizmadia, Eva, Candotti, Fabio, Nadeau, Kari, Bouma, Gerben, Delmonte, Ottavia M., Frugoni, Francesco, Fomin, Angela B. Ferraz, Buchbinder, David, Lundequist, Emma Maria, Massaad, Michel J., Tsokos, George C., Hartwig, John, Manis, John, Terhorst, Cox, Geha, Raif S., Snapper, Scott, Lang, Karl S., Malley, Richard, Westerberg, Lisa, Thrasher, Adrian J., Notarangelo, Luigi D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2012
Pynciau:
Immunobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327460/
https://ncbi.nlm.nih.gov/pubmed/22302739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-379412
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