B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

Wiskott Aldrich syndrome (WAS) is caused by mutations in the WAS gene that encodes for a protein (WASp) involved in cytoskeleton organization in hematopoietic cells. Several distinctive abnormalities of T, B, and natural killer lymphocytes; dendritic cells; and phagocytes have been found in WASp-def...

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Detalhes bibliográficos
Principais autores: Recher, Mike, Burns, Siobhan O., de la Fuente, Miguel A., Volpi, Stefano, Dahlberg, Carin, Walter, Jolan E., Moffitt, Kristin, Mathew, Divij, Honke, Nadine, Lang, Philipp A., Patrizi, Laura, Falet, Hervé, Keszei, Marton, Mizui, Masayuki, Csizmadia, Eva, Candotti, Fabio, Nadeau, Kari, Bouma, Gerben, Delmonte, Ottavia M., Frugoni, Francesco, Fomin, Angela B. Ferraz, Buchbinder, David, Lundequist, Emma Maria, Massaad, Michel J., Tsokos, George C., Hartwig, John, Manis, John, Terhorst, Cox, Geha, Raif S., Snapper, Scott, Lang, Karl S., Malley, Richard, Westerberg, Lisa, Thrasher, Adrian J., Notarangelo, Luigi D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327460/
https://ncbi.nlm.nih.gov/pubmed/22302739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-379412
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