Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function

The Wiskott-Aldrich syndrome protein (WASP) is a key cytoskeletal regulator of hematopoietic cells. Although WASP-knockout (WKO) mice have aberrant B-cell cytoskeletal responses, B-cell development is relatively normal. We hypothesized that N-WASP, a ubiquitously expressed homolog of WASP, may serve...

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Detalhes bibliográficos
Main Authors: Westerberg, Lisa S., Dahlberg, Carin, Baptista, Marisa, Moran, Christopher J., Detre, Cynthia, Keszei, Marton, Eston, Michelle A., Alt, Frederick W., Terhorst, Cox, Notarangelo, Luigi D., Snapper, Scott B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350364/
https://ncbi.nlm.nih.gov/pubmed/22411869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-308197
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