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Regulation of Alveolar Epithelial Na(+) Channels by ERK1/2 in Chlorine-Breathing Mice

The mechanisms by which the exposure of mice to Cl(2) decreases vectorial Na(+) transport and fluid clearance across their distal lung spaces have not been elucidated. We examined the biophysical, biochemical, and physiological changes of rodent lung epithelial Na(+) channels (ENaCs) after exposure...

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Detalhes bibliográficos
Main Authors: Lazrak, Ahmed, Chen, Lan, Jurkuvenaite, Asta, Doran, Stephen F., Liu, Gang, Li, Qian, Lancaster, Jack R., Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326429/
https://ncbi.nlm.nih.gov/pubmed/21997487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0309OC
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