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Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity

The human cystic fibrosis transmembrane conductance regulator (CFTR) is a cyclic AMP-activated chloride (Cl(−)) channel in the lung epithelium that helps regulate the thickness and composition of the lung epithelial lining fluid. We investigated whether influenza M2 protein, a pH-activated proton (H...

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Detalhes bibliográficos
Main Authors: Londino, James D., Lazrak, Ahmed, Jurkuvenaite, Asta, Collawn, James F., Noah, James W., Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652020/
https://ncbi.nlm.nih.gov/pubmed/23457187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00314.2012
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