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Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity
The human cystic fibrosis transmembrane conductance regulator (CFTR) is a cyclic AMP-activated chloride (Cl(−)) channel in the lung epithelium that helps regulate the thickness and composition of the lung epithelial lining fluid. We investigated whether influenza M2 protein, a pH-activated proton (H...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652020/ https://ncbi.nlm.nih.gov/pubmed/23457187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00314.2012 |
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