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Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung

We sought to establish whether the cystic fibrosis transmembrane conductance regulator (CFTR) regulates the activity of amiloride-sensitive sodium channels (ENaC) in alveolar epithelial cells of wild-type, heterozygous (Cftr(+/−)), knockout (Cftr(−/−)), and ΔF508-expressing mice in situ. RT-PCR stud...

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Bibliografiske detaljer
Main Authors: Lazrak, Ahmed, Jurkuvenaite, Asta, Chen, Lan, Keeling, Kim M., Collawn, James F., Bedwell, David M., Matalon, Sadis
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191758/
https://ncbi.nlm.nih.gov/pubmed/21743028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00094.2011
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