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Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung

We sought to establish whether the cystic fibrosis transmembrane conductance regulator (CFTR) regulates the activity of amiloride-sensitive sodium channels (ENaC) in alveolar epithelial cells of wild-type, heterozygous (Cftr(+/−)), knockout (Cftr(−/−)), and ΔF508-expressing mice in situ. RT-PCR stud...

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Detalhes bibliográficos
Main Authors: Lazrak, Ahmed, Jurkuvenaite, Asta, Chen, Lan, Keeling, Kim M., Collawn, James F., Bedwell, David M., Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191758/
https://ncbi.nlm.nih.gov/pubmed/21743028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00094.2011
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